Genetic structure of Patagonian toothfish populations from otolith DNA

first_imgThe Patagonian toothfish, Dissostichus eleginoides, is a valuable fishery species and has a discontinuous distribution across the Southern Ocean. Identification of the genetic stock structure of toothfish would allow evaluation of the suitability of the spatial scale at which fisheries management operates. Genetic subdivision seems likely given the species distribution. Population genetics studies of this species have been performed; however, they have been limited by sample size, spatial coverage and/or the type of markers investigated. As a potential solution, we developed methods for extracting toothfish DNA from otoliths that are available in large numbers from collections held at several research institutes. Genetic differentiation between the three oceanic sectors was investigated. Four mitochondrial and four nuclear markers with multiple single nucleotide polymorphisms were sequenced by high throughput sequencing for samples from six locations. Genetic differentiation was found between three sectors with nuclear markers. However, only the Pacific sector was differentiated from other sectors with mitochondrial markers. This study demonstrates the usefulness of otolith DNA as a means of increasing sample sizes for population genetics research of fish. Additionally, the combination of nuclear and mitochondrial markers may allow insight into how the observed differences in movements between male and female toothfish impact population structure.last_img read more

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Eating with Grace Website Launched

first_imgEating With Grace” creator, Anya Raven Hunter, LICSW, offers womens therapy groups and other services (individual counseling and coaching, phone and email consults, consultation and referral) to individuals over 18 who struggle with food, weight and body image issues. Anya also gives talks to community organizations and other health care providers about compulsive overeating.The Eating with Grace website also offers information about eating disorders and contact information for other Vermont and national resources.Anya Raven Hunter is a Licensed Clinical Social Worker and Body-Mind Psychotherapist in Montpelier, Vermont. She has been in private practice since 1986.last_img read more

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Scatec Solar starts commercial operation at first phase of 258MW South African solar park

first_imgScatec Solar starts commercial operation at first phase of 258MW South African solar park FacebookTwitterLinkedInEmailPrint分享PV Tech:Scatec Solar and its partners have both grid connected and reached commercial operation for the 86MW first phase of a 258MW PV installation in Upington, South Africa. The first phase of the project, known as Sirius, is expected to generate 217 GWh of renewable energy and cut down on more than 180,000 tonnes of CO2 emissions annually.The solar facility in Upington, which will be comprised of three total phases, was awarded back in April 2015 through the fourth bidding round of the Renewable Energy Independent Power Producer Programme (REIPP) in South Africa.Ownership of the plant is split between Scatec Solar (42%), Norfund (18%), South African investor H1 Holdings (35%) and the surrounding community of Upington (5%).The remaining two phases of the installation, featuring a combined installed capacity of 172MW, are expected to reach commercial operation over the next couple of months.South Africa has continued to allocate more and more resources toward expanding its renewable-energy sector, especially thanks to a number of measures taken over the last couple of months. Back in October 2019, the country’s Department of Mineral Resources and Energy (DMRE) signed off on a ruling to set aside 6GW of new large-scale solar over the next decade, with this new Integrated Resource Plan (IRP) allocating the capacity in 1GW instalments each year in 2022, 2023, 2025 and from 2028-30. South Africa had already committed solar allocations of 114MW in 2020, 300MW in 2021, and 400MW in 2022.[Conor Ryan]More: Scatec Solar completes first phase of 258MW PV project in South Africalast_img read more

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Medford Christmas Eve Home Invasion Suspect Sought

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York Suffolk County police released a sketch Wednesday of a suspect wanted for an armed home invasion in Medford on Christmas Eve.The man in the sketch knocked on the door of a Sipp Avenue home and when a resident answered the door, the suspect flashed a silver handgun and forced his way inside on Dec. 24, police said.The burglar stole cash, a laptop computer and a cellphone before fleeing the scene, police said.The suspect in the sketch was described as a black man, 25 to 30 years old, 5-feet, 9-inches to 5-feet, 10-inches tall, 180 to 200 pounds with a beard and mustache. He was wearing a baseball cap with a gray hooded sweatshirt, gray sweat pants and brown and green Timberland boots.Sixth Squad detectives ask anyone with information about this crime to call Crime Stoppers anonymously at 1-800-220-TIPS.  All calls will be kept confidential. A cash reward of up to $5,000 is being for information that leads to an arrest.last_img read more

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Long Island Rattlesnake Bites Manorville Man on Eyelid

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York A 22-year-old Manorville man bitten by a pet diamondback rattlesnake last week will likely suffer permanent injuries as a result of the bite, the Suffolk County SPCA said. The unidentified man was bitten in the eyelid last Friday morning but didn’t call 911 until the evening, according to Suffolk SPCA Chief Roy Gross. The man apparently passed out after the snake attack. It’s unclear how long he was unconscious. “He’s lucky he didn’t die,” Gross said.The man owned two pet rattlesnakes, Gross said. The one that bit him is a two-foot long diamondback rattlesnake, and the other, a prairie rattlesnake, is 16 inches long. Rattlesnakes are illegal to own as pets. However, rattlesnakes can be kept legally for educational purposes, but only if a person or organization obtains a license. Gross, who in recent years has dealt with an influx of alligators located in various Suffolk County communities, warned residents that rattlesnakes are extremely dangerous and should under no circumstances be kept as pets. “Stay away from these [reptiles],” he said. “There’s a reason why they’re illegal; they’re unpredictable and they can be deadly.” The man was bitten by a rattlesnake with “enough venom” to kill an adult, Gross noted. The Suffolk SPCA and New York State Department of Environmental Conservation took possession of the snake and sent it to a reptile sanctuary out of state, officials said. “Abandoned and dangerous reptiles and amphibians have become an all too common occurrence here on Long Island,” said Peter A. Scully, director of the DEC’s Long Island region. “All too often, individuals do not realize the difficulties and complications that arise from owning one of these animals.”It’s unclear how the man acquired the snakes.Gross asked residents to call the Suffolk SPCA 631-382-7722 or DEC at 1-877-457-5680 if they have information regarding anyone supplying rattlesnakes.last_img read more

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You can’t manage what you don’t measure: Part three

first_img 6SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Buddy Kittle Buddy Kittle is the Co-Founder of Banker’s Mortgage Consulting, LLC. He began his mortgage banking career in 1993 as a Mortgage Loan Officer and later promoted to producing manager … Web: bankersmortgageconsulting.com Details This being the final article of a three part series I encourage you to read part one and part two. The purpose of sharing this specific outline is to improve the borrower experience, increase profitability and gain additional market share in mortgage lending.Observations:Most of us are familiar with the saying “work on your business not in your business”, I have to wonder if this saying was created by a mortgage professional? It is very easy for the mortgage manager to be consumed in day to day activity thus not working on the growth of their department.We realize that the mortgage manager either has difficulty delegating or doesn’t have the appropriate staff in place to execute properly. It is important for senior management to recognize this and make corrective actions to assist the mortgage manager for the success of the entire department.This is a common occurrence we observe during site visits. Normally there are production goals set by the manager and senior management and over the last years of low rates the goals may have been met or exceeded. With the inevitable increase of interest rates on the horizon mortgage managers need to be working on their business to develop new strategies to increase loan volume, reduce time from application to clear to close and increase profitability.Solutions:The key component to develop more business in a rising rate environment is reducing the time from application to clear to close. If you are approving loans faster than your peer group then referrals will increase from industry partners. There is a book titled “It’s Not the Big that Eat the Small, It’s the Fast that Eat the Slow”, this title certainly applies to mortgage lending.The mortgage manager has to focus on the efficiencies of their operation. To be efficient they have to measure every step of the operation. Loan officers, processors, underwriters and loan closers should have report cards that track the performance of each position. When implemented properly reports can be generated that give live time overviews of status of each loan and the entire departments performance.Recently I visited with a CEO and asked them how they measured the efficiency of their mortgage operation. He stated “I receive reports at the end of the month that tell me how long it took to close loans, how much volume was closed and our gain on sale for the month”. Measuring performance after the loan has closed is similar to driving to Florida and then checking map quest or your GPS to make sure you took the best route.Mortgage managers have a very difficult job managing a business that has so many variables. Loan origination systems (LOS) that deliver great reports, track status of each loan and number of team member touches is the start to realizing where there is room for improvement. The mortgage manager must be monitoring performance of the sales and support staff on a daily basis with these reports.It is necessary that the senior management allow the mortgage manager to manage the operation. They should make sure they are properly staffed and have strategic plans in place for long and short term growth. Additionally, there should be an implementation timeline that parallels the strategic plan. Frequent meetings should be scheduled to review the progress of the plan and implementation and to see if adjustments need to be made based on a fast changing industry. We find that operations that include their staff in positive meetings to review current processes and discuss new ideas on how to improve the workflow gives them a feeling of ownership thus motivating them to perform at a higher level.Review:There is nothing easy when your goal is be become the best mortgage operation in your area however it can be done with a clear vision, strategic planning and accountability of everyone in the department.As mentioned in the previous articles the CEO and/or senior management have to embrace the business model and let everyone know they are supporting the new changes for success. The success or failure has a lot to do with senior management vocalizing to the team members their support.The following points need to be considered when building a successful operation:Proper education, educate, empower and hold accountable your team membersStrategic plan with implementation timelinesFrequent meetings to review current workflows and technology for improvement with entire departmentProper procedures and workflows understood by all team membersRobust LOS set up correctlyGreat dashboard reporting to view status daily of the departmentTracking the KPIs of each team members position and operation for efficiencyA manager that delegates and manages the operation as opposed to working in the businessSenior management/CEO vocalizing their support of the business model to the entire departmentThis is just a very short list that will help you take your department to the next level. Once again the statement below says it all:“You can’t manage what you don’t measure, to be brief measure, monitor and manage”!I wish you the best of success and if you need further assistance give us a call or email.last_img read more

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Larsa Pippen Says She’s Fighting COVID-19 Amid Kardashian Rift

first_imgLarsa Pippen revealed that she’s been sick with the novel coronavirus after making headlines for her hot takes on the Kardashian family — but she quickly deleted the announcement.“I’ve been battling Covid for a week. It’s no joke I’ve never felt pain like this!” the Real Housewives of Miami alum, 46, wrote on her Instagram Story on Friday, November 13, before removing the post hours later.Larsa Pippen attends the ROC Nation Pre-Grammy Brunc Larsa Pippen Says She Tested Positive for COVID-19 Amid Kardashian DramaLarsa Pippen attends the ROC Nation Pre-Grammy Brunch in Los Angeles on February 9, 2019. Broadimage/Shutterstock- Advertisement – Us Weekly can confirm that the reality TV personality tested positive for COVID-19 as the global health crisis rages on. “She’s been battling it for a week with a hard time breathing,” Pippen’s rep said. “She’s had horrible body aches. We’re hoping she starts feeling better soon.”Pippen’s health revelation comes shortly after she came clean about the state of her current relationship with Kim Kardashian, Kourtney Kardashian and Khloé Kardashian amid rumors that the longtime pals had a falling out. While discussing her history with the famous family, Pippen called out Kanye West for being the reason for her feud with Kim, 40.“If Kanye feels like him and Kim are better without me, then let them be without me. I’m OK with that,” Pippen said on the Monday, November 9, episode of the “Hollywood Raw” podcast, before claiming that the Yeezy designer, 43, had “brainwashed” his wife and her sisters.Kim Kardashian Khloe Kardashian and Kourtney Kardashian in 2014 Larsa Pippen Says She Tested Positive for COVID-19 Amid Kardashian DramaKim Kardashian, Khloe Kardashian and Kourtney Kardashian attend the Grand Opening of DASH Miami Beach on March 12, 2014. Omar Vega/Invision/AP/Shutterstock- Advertisement – Though the details of their friendship’s demise raised eyebrows, the Kardashian family is “unbothered” by Larsa’s comments.“The family thinks Larsa spoke out about this now because she is craving attention,” a source told Us exclusively. “And the only attention she got as of late was from being Kim’s best friend and from being on the show.”Listen to Us Weekly’s Hot Hollywood as each week the editors of Us break down the hottest entertainment news stories! Earlier this year, fans noticed that the Skims founder was no longer following Pippen on Instagram after years of friendship. The Chicago native, who was previously married to Scottie Pippen for 21 years, had frequently appeared on Keeping Up With the Kardashians since falling in with the reality stars and their squad.As social media users wondered whether a feud was brewing, an insider told Us in July that Kim “wanted to reset” her account to focus on “her family and childhood friends.” Larsa, however, continued to accuse West of being the instigator behind the end of her friendship with Kim.“I didn’t feel any type of way. I just felt, like, do what’s best for your family,” she said of the KKW Beauty founder on Monday. “I love you, you and I are best friends, we’ve been through everything together, I would never do anything to jeopardize our relationship, we’re like sisters, we’re family, but if you have to unfollow me to make your home a better place, do it.”- Advertisement – – Advertisement –last_img read more

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A tale of two Japanese drugs in tests to fight COVID-19

first_imgTopics : In the global hunt for coronavirus treatments, a Japanese antiviral medicine known as Avigan has won plaudits from Prime Minister Shinzo Abe and $128 million in government funding.But it’s not the only game in town.Camostat, a 35-year old pancreatitis drug made by Osaka-based Ono Pharmaceutical Co, has captured the interest of scientists in Japan and overseas with little fanfare or state assistance. Abe’s administration has pledged to give away free supplies of the drug, with some 43 countries making formal requests. Fujifilm chairman Shigetaka Komori is a longtime backer of Abe, though the cabinet has denied there is any connection between their relationship and the government’s promotion of Avigan.The use of Avigan is decided by doctors and its approval will depend on medical and scientific evaluation in due course, said Fujifilm spokeswoman Kana Matsumoto.”The use of Avigan has nothing to do with the relationship between the Prime Minister and any particular company,” she said.Destructive to fetuses Avigan, known generically as favipiravir, was developed in the late 1990s by a company that was later purchased by Fujifilm as part of its transition from photo businesses to healthcare. The drug works by short-circuiting the reproduction mechanism of certain RNA viruses such as influenza.Avigan can be taken as a pill, which would make it more accessible than Gilead’s remdesivir, currently administered only as an intravenous infusion. But the mechanism that makes Avigan effective against viruses also makes it destructive to the rapid cell growth of fetuses.After being tested against a range of viruses, Avigan was finally approved in Japan in 2014, but only for emergency use against flu epidemics, and it was licensed in China where it has since gone off patent.Also clinically unproven is a camostat mesylate. Developed by Ono Pharmceutical, most famous for its blockbuster Opdivo cancer drug, camostat is a protease inhibitor that has been used primarily to treat pancreatitis and some types of cancer. But past laboratory and animal tests against SARS-CoV-1 showed it has antiviral functions, and it can be safely administered in high enough doses to match the concentrations that were effective in the lab.A study published in the scientific journal Cell in March found that camostat blocks an enzyme essential for the entry of the coronavirus into the lungs, drawing researchers’ interest. One of them was Dr. Joseph Vinetz, a professor at the Yale School of Medicine, who is ready to launch a clinical trial of camostat.”It’s got a 35-year track record, so it seemed to be a very safe drug,” he said. “I said we’ve got to try it. I’m a physician and we’re desperate for anything we can give to people.”Vinetz is still trying to raise money for the trial.”I’m 100% certain that we needed to start this trial a month ago. And we can have a definitive result in a month.”Ono launched camostat, known commercially in Japan as Foipan, as a treatment for chronic pancreatitis in 1985 and postoperative reflux esophagitis in 1994. The company is now supplying the drug for COVID-19 studies in Japan and overseas, according to spokesman Yukio Tani.Itzchak Levy at the Sheba Medical Center in Israel launched a self-funded camostat trial in April. “Up to now we recruited 14 patients and look forward to further recruitment,” Levy said.Another trial being carried out at the University of Kentucky is testing whether camostat can inhibit the virus’s preferred pathway into human cells, and with hydroxychloroquine – the malaria drug touted by Trump — also block the back door, boosting the treatment’s effectiveness.Existing science behind camostat’s mechanism of action and tolerance in patients “is why we were enthusiastic about its potential,” said Elijah Kakani, an assistant professor at the university involved in the research. “However, at this point we need to temper our enthusiasm and be objective in our evaluation of this medication for the problem at hand.” center_img The two compounds are among dozens undergoing testing around the globe and illustrate how the race to develop treatments and vaccines is still wide open despite politicians such as Abe and US President Donald Trump promoting the potential benefits of certain drugs.Gilead Science Inc’s remdesivir has pulled into the lead after promising early trial results prompted emergency approval in the United States and Japan. While remdesivir has shown promise in reducing recovery times of hospitalized patients, the search continues for additional treatment options.Interest in Avigan soared in March after a Chinese official said that it appeared to help patients recover from COVID-19, the flu-like infection caused by the coronavirus. It is now the subject of at least 14 clinical trials. Amidst a global rout in stocks, shares in Fujifilm have shot to record highs.Abe has called for Avigan to be approved for use by the end of this month if these trials are effective – unprecedented speed, particularly for a drug known to cause birth defects.last_img read more

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Marc Overmars tips Alexis Sanchez to leave Manchester United and make sensational Arsenal return

first_imgAdvertisement Overmars made a bold claim (Picture: VI Images via Getty Images)But the Ajax director of football believes the door could still be open for him to make a sensational return to north London because Arsenal have failed to replace him.AdvertisementAdvertisementADVERTISEMENT‘I have great respect for Alexis, because he did extremely well in Arsenal, I do not know if it was a good decision to leave,’ he told ADN Deportes.‘English football changes you, it turns you around, it took me a step forward. Arsene Wenger arrived a year before me, Dennis Bergkamp made a big impression in England, it was a fantastic time, I think we changed the history of the club a bit.More: Manchester United FCRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starNew Manchester United signing Facundo Pellistri responds to Edinson Cavani praiseEx-Man Utd coach blasts Ed Woodward for two key transfer errors‘This type of players were very important for Arsenal, because that’s where they take you to focus, after Alexis, Arsenal tried to sign another player like that, but he was not given, so he could go back to Arsenal.’Manchester United would no doubt be keen to offload the Chilean – who is their highest earner. Whether Arsenal would be willing to welcome Sanchez back is another question.Should Arsenal re-sign Alexis Sanchez?Yes0%No0%Share your resultsShare your resultsTweet your results Advertisement Comment Sanchez has struggled at United (Picture: Getty Images)Marc Overmars believes the door would be open for Alexis Sanchez to return to Arsenal after a disappointing spell at Manchester United.The Chile international has struggled to produce his best form at Old Trafford since leaving the Emirates more than a year ago and the 30-year-old is set to cut an unhappy spell in Manchester short.Overmars, who won the Premier League and FA Cup during a three-year stay at Highbury under Arsene Wenger, has ‘great respect’ for Sanchez but believes he may have been mistaken to ditch the Gunners in favour of a move to the north of England. Metro Sport ReporterFriday 15 Feb 2019 7:45 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link1.5kShares Marc Overmars tips Alexis Sanchez to leave Manchester United and make sensational Arsenal returnlast_img read more

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Teacher Tom gives the boys a lesson

first_img2nd Sonny 40pts3rd Brian Wilkinson (15) 38ptsThe day was fresh and cool (by Pattaya standards anyway) and we set off with 2 van loads of golfers to our regular Monday venue of Green Valley.  The course was in great condition save for 2 temporary tee boxes, so there were no excuses allowed for not shooting your handicap, but not many did.  The wind played havoc with many of the players.  Tommy Balch was in fine form by any standards and turning the big 70 a couple of weeks ago may have given him the incentive needed to grab the top spot this week.  The great thing about this game is that we are all able to compete on a level playing field and with all ages, and only the game of golf allows this.Marlene Prudden and Kevin Moraghan – winners on the Kabinburi road trip.The story of the day was the driving of Mark Reid.  Not on the course, but behind the wheel!  This being the first time in 30 years Mark has driven a “stick shift” as the Colonials put it, or a “manual” transmission, there was a trace of apprehension in the air as we drove off from the club.  We were all prepared to bellow out “grind it til ya find it” but there was no need for our standard lines of abuse as Mark, or “Robbie” as he is know on the Soi Dao Karaoke circuit, did a perfect job of guiding our pristine new Toyota Commuter through Pattaya’s worst lanes and down the old 36 to the course.  Fine job mate and thanks again.Wednesday, Dec. 21, Treasure Hill (yellow tees) – Stableford1st Chris Parr (18) 38pts2nd Warren Holland (25) 32ptsIt was par for the course for Chris today as he bettered the field by 6 strokes.  The affable Englishman kept it in the fairway all day and avoided the trouble that Treasure Hill is famous for.Nat, Koi, Raju and Ying wish you all a Happy New Year!The crocodile course is a favourite of The Golf Club these days as the grounds crew have really gotten their act together and have the course in lovely condition.  It has always been a difficult layout but it is also one of the most interesting in the Pattaya area.Friday, Dec. 23, Century Chonburi (white tees) – Stableford1st Steve Ellison (17) 37pts2nd Dave Shelton 35pts3rd Marlene Prudden 33ptsYes, you read it right, Century Chonburi.  Now I know that many avid readers probably have not played here in ages or not even been out here at all.  Just finding the place takes some doing and the roads in are bumpy and winding.  That said, one must remember the high season green fees here are a jaw dropping 200 baht. Two Hundred Baht, let’s see…that translates to 6 bucks and sixty cents US or 4 quid Sterling.  That is amazing for a Sir Nick Faldo designed course.Century Chonburi – a bargain!We had a great day out and part of it was the expectation that it would be a fun day of golf with a ‘lift, clean and place’ proviso which was the correct policy on this course.  Don’t expect too much of this track as the maintenance crew is doing all they can with the budget they have.  They are doing a great job under difficult conditions.  In fact, the back nine was really good, an extremely enjoyable layout in decent shape that proved a good finish.   All the bunkers were groomed properly and played fair.  The greens were also in very good nick but the saucering made them a tough read for putts from the outside.Steve Ellison finally had a good day off the tee and the driver took him to the top of the podium with 37 points on a course never played before.  Likewise for Dave Shelton who was just off the pace with 35 and a gaggle of golfers on 33 with the count back won by the ageless Marlene Prudden with 21 points on the back.  She beat Vancouverite Courtney Bailey and hubby Brian Prudden for 3rd place.Facilities here are very basic with 5 showers (20 baht for towel & soap) tiny lockers (bring your own lock) no food on the course etc. but it sure would be interesting to see Century Chonburi with 30 million baht pumped into her!  18 out of 20 of our golfers had a great day out and would come back, so get out there and see for yourself before you make any decisions.Thanks for a great 2011!The staff and partners of The Golf club would like to thank you all for your support over the past 12 months and wish you and your family a happy and healthy year ahead of us in 2012.  Happy New Year!With Bob, Jez, Lee and Lou up at Mt. Everest, we forgot to get our write-up in on time but would now like to report that our Kabinburi road trip the previous week was won by Brian & Marlene Prudden on the first day and Kevin Moraghan & Marlene Prudden on the second day.  Marlene is getting more press time than Paris Hilton these days.  Well played girl!  A full report on the Everest expedition will be coming soon so watch this space!Note:  The Golf Club is located on Soi LK Metro and we play on Monday, Wednesday and Friday so come join us for a fun day out.  Just call 085 434 3377 or see website www.golfclubpattaya.com and for more information mail: [email protected] PSC golf from The Golf ClubMonday, Dec. 19, Green Valley (white tees) – Stableford1st Tom Balch (27) 41ptslast_img read more

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