Alplaus development will be harmful to town

first_imgCategories: Letters to the Editor, Opinion As a resident of Alplaus since 1977, I am firmly against the proposed Prime Mohawk development of 228 units. This development would more than double the population of Alplaus. It in no way would be beneficial or compatible with the surrounding land uses.Alplaus is a lovely, quiet, walking hamlet, where we enjoy a neighborly lifestyle. Besides doubling our population, this development would greatly increase traffic and destroy a beautiful section of the Mohawk River shoreline that is zoned land conservation.Maybe that doesn’t mean anything to the developer, or even to the Glenville Town Board, but it’s why many of us set down roots here. The addition of this monstrous development makes no sense.The town supervisor has repeatedly told us that the reason for this high-density project is to offset the cleaning of a brownfield where the Mohawk Industrial Park now sits. I firmly believe that it is the present owner’s responsibility to clean this site. The contamination there is well documented, and he has known about it for years. Passing the buck to a builder and then having Alplaus residents deal with the aftermath is shameful.We welcome responsible development with forethought and mindfulness to preserve our hamlet’s integrity as well as its natural surroundings.Kathleen BoyleAlplausMore from The Daily Gazette:Schenectady County warns of possible COVID-19 exposure at Schenectady restaurant, Rotterdam barLocal movie theater operators react to green lightFoss: Should main downtown branch of the Schenectady County Public Library reopen?EDITORIAL: Urgent: Today is the last day to complete the censusEDITORIAL: Thruway tax unfair to working motoristslast_img read more

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Letters to the Editor for Wednesday, July 3

first_imgCategories: Letters to the Editor, OpinionTrump’s economy trumps Obama’sI felt compelled to respond to Mr. Guido’s June 1 letter of criticism of my comments and President Trump’s economy.Only in Democrat circles is an economy growing at 1.5 percent better than an economy growing at 3 percent. The better economy of Obama’s had the lowest labor participation rate ever. Under Trump, we are at all time high percentages. Don’t tell the black and Hispanic communities how bad things are. The unemployment rates in both communities are at all-time lows. Under Obama, more than 46 million Americans were on food stamps. Today, 42 million Americans are.Mr. Guido sited how well he did with his investments during Obama’s reign. The stock market did in fact do well, but not because the economy was strong. It in fact was struggling due to Obamacare and a rabid EPA. Rather, the compliant Fed pumped trillions of dollars into the economy and with interest rates kept artificially low, the stock market was the only place to put money for investments.Mr. Guido, do you remember Biden talking up the summer of recovery? What a joke. It never came.I love hearing Obama and Biden taking credit for this economy. What a farce. It wasn’t until we got a politically incorrect businessman who didn’t need the job and was willing to take a pay cut because he loves this country did we get on our feet.We are lucky to have Donald J. Trump as our president.Dave EdwardsHalfmoonOlder drivers need retesting for safetyEvery year at the beginning of summer, I dread turning the pages in the newspaper to read about another person being killed or seriously injured in a motorcycle accident.Most of the time, speed was a factor. But in other incidences, the fault of the accident was not the motorcyclist’s, but the automobile driver’s.The driver of the car may not have seen the single rider and may have pulled out in front of the motorcyclist or cut them off.In too many of the accidents, the auto driver is an older American. I think there should be a law that mandates when adults turn 70 years old, an updated driving test is required.The goal isn’t to revoke licenses, but to make the roads safer for everyone.Sunnyview Rehabilitation Hospital offers evaluation services for elderly drivers. For more information on the program call 518-386-3601.Mitch WalshNorth GreenbushMore from The Daily Gazette:EDITORIAL: Find a way to get family members into nursing homesEDITORIAL: Beware of voter intimidationEDITORIAL: Thruway tax unfair to working motoristsEDITORIAL: Urgent: Today is the last day to complete the censusFoss: Should main downtown branch of the Schenectady County Public Library reopen?last_img read more

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Oliver twists Teesland

first_imgTo access this article REGISTER NOWWould you like print copies, app and digital replica access too? SUBSCRIBE for as little as £5 per week. Would you like to read more?Register for free to finish this article.Sign up now for the following benefits:Four FREE articles of your choice per monthBreaking news, comment and analysis from industry experts as it happensChoose from our portfolio of email newsletterslast_img

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Laing’s £11.4m SW1 sale

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Fight for City fringe heats up

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German bribes scandal hits JLL

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Nineteen dead, 139 infected with coronavirus in Iran: Health ministry

first_imgSeveral of Iran’s neighbors have closed their borders and banned flights from Iran due to fears over the virus, which could hurt the Islamic Republic’s already fragile economy.Kuwait, Iraq, Bahrain, Oman, Lebanon, the United Arab Emirates and Afghanistan have all reported cases of coronavirus involving people who traveled to Iran.President Hassan Rouhani said on Wednesday that coronavirus must not become an enemy weapon that prevents business in Iran, according to the official presidency website.Iran’s economy has been battered since the United States withdrew from a multilateral nuclear deal in 2018 and reimposed sanctions on Tehran.”Corona should not be turned into a weapon of our enemies for shutting down work and production in the country,” Rouhani said. “The Americans and our enemies during this time, around two years of which have passed, have wanted, with their sanctions and propaganda, to shut down production and economic activities in this country and for the people to suffer.” Topics : Nineteen people have died and 139 people have been infected by coronavirus in Iran, health ministry spokesman Kianush Jahanpur said on Wednesday in an announcement on state TV.Iran has had the highest number of deaths from coronavirus outside China, where the virus emerged in late 2019.Iranian officials announced the first deaths and infections from coronavirus in the Islamic Republic last week, and the spike in numbers in a short period of time has led Iranians to criticize authorities online and accuse them of a cover-up, a charge officials have denied.last_img read more

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France warns against handshakes as corona infections soar

first_imgVeran called on citizens to help stop the spread of the virus by respecting authorities’ safety instructions.“Protect yourself and your loved ones,” he said.Separately, Defense Minister Florence Parly said on her Twitter feed that several confirmed coronavirus infections had been reported on the military base of Creil, north of Paris.French President Emmanuel Macron’s office said on Friday that the government will meet on Saturday to discuss the health crisis.On Thursday, the health ministry had reported 38 cases of coronavirus in France, of which two people had died, 12 were cured and 24 were hospitalized, with two of those being in a “serious condition”.Topics : French authorities on Friday recommended that people refrain from shaking hands to prevent infection from the coronavirus as the number of confirmed cases jumped by 19 to 57.France will also keep several schools in the Oise area north of Paris closed after holidays end on Sunday in order to halt the spread of the virus, Health Minister Olivier Veran said.“The virus is now circulating on our territory … I recommend that, for now, people do not shake hands,” Veran told reporters at a daily briefing about the outbreak.last_img read more

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Starved sports fans to get feast of competitive eating

first_imgOver a gallon of baked beans must be rapidly consumed for a place in the finals, where the first to finish 10 individual cups of ramen noodles will be crowned the champion.The competition will feature $11,500 in prize money, with $5,000 going to the winner.MLE and BetOnline.ag will also donate $10,000 to Feeding America, a hunger relief organization.  “Competitive eating is most powerful when conducted on-stage in front of a large audience, but it is also one of the few sports that professionals can perform from the confines of their own home,” MLE Chairman George Shea said in a statement.”While there has been substantial discussion about which professional sport would be the first to return – with baseball, basketball, golf and MMA all floating recent potential return plans – competitive eating is first to come back,” he said.”It is a powerful statement of American resilience.”The qualifying round will consist of 907 grams of sliced bologna while the quarterfinals will feature one family pack of Oreo cookies and a half gallon (1.9 liters) of milk. Topics :center_img While many Americans self-isolating during the coronavirus crisis have found comfort in frequent trips to the refrigerator, the pros are ready to make those who have overindulged feel better about themselves when they compete in a tournament starting Friday.Major League Eating on Tuesday said it would return to action with the BetOnline Quarantine Challenge, a bracket-style elimination tournament with eight of the world’s top competitive eaters facing off via video from their homes.The competition, which will feature male and female world number ones Joey Chestnut and Miki Sudo, will be carried on MLE’s YouTube channel.last_img read more

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A tale of two Japanese drugs in tests to fight COVID-19

first_imgTopics : In the global hunt for coronavirus treatments, a Japanese antiviral medicine known as Avigan has won plaudits from Prime Minister Shinzo Abe and $128 million in government funding.But it’s not the only game in town.Camostat, a 35-year old pancreatitis drug made by Osaka-based Ono Pharmaceutical Co, has captured the interest of scientists in Japan and overseas with little fanfare or state assistance. Abe’s administration has pledged to give away free supplies of the drug, with some 43 countries making formal requests. Fujifilm chairman Shigetaka Komori is a longtime backer of Abe, though the cabinet has denied there is any connection between their relationship and the government’s promotion of Avigan.The use of Avigan is decided by doctors and its approval will depend on medical and scientific evaluation in due course, said Fujifilm spokeswoman Kana Matsumoto.”The use of Avigan has nothing to do with the relationship between the Prime Minister and any particular company,” she said.Destructive to fetuses Avigan, known generically as favipiravir, was developed in the late 1990s by a company that was later purchased by Fujifilm as part of its transition from photo businesses to healthcare. The drug works by short-circuiting the reproduction mechanism of certain RNA viruses such as influenza.Avigan can be taken as a pill, which would make it more accessible than Gilead’s remdesivir, currently administered only as an intravenous infusion. But the mechanism that makes Avigan effective against viruses also makes it destructive to the rapid cell growth of fetuses.After being tested against a range of viruses, Avigan was finally approved in Japan in 2014, but only for emergency use against flu epidemics, and it was licensed in China where it has since gone off patent.Also clinically unproven is a camostat mesylate. Developed by Ono Pharmceutical, most famous for its blockbuster Opdivo cancer drug, camostat is a protease inhibitor that has been used primarily to treat pancreatitis and some types of cancer. But past laboratory and animal tests against SARS-CoV-1 showed it has antiviral functions, and it can be safely administered in high enough doses to match the concentrations that were effective in the lab.A study published in the scientific journal Cell in March found that camostat blocks an enzyme essential for the entry of the coronavirus into the lungs, drawing researchers’ interest. One of them was Dr. Joseph Vinetz, a professor at the Yale School of Medicine, who is ready to launch a clinical trial of camostat.”It’s got a 35-year track record, so it seemed to be a very safe drug,” he said. “I said we’ve got to try it. I’m a physician and we’re desperate for anything we can give to people.”Vinetz is still trying to raise money for the trial.”I’m 100% certain that we needed to start this trial a month ago. And we can have a definitive result in a month.”Ono launched camostat, known commercially in Japan as Foipan, as a treatment for chronic pancreatitis in 1985 and postoperative reflux esophagitis in 1994. The company is now supplying the drug for COVID-19 studies in Japan and overseas, according to spokesman Yukio Tani.Itzchak Levy at the Sheba Medical Center in Israel launched a self-funded camostat trial in April. “Up to now we recruited 14 patients and look forward to further recruitment,” Levy said.Another trial being carried out at the University of Kentucky is testing whether camostat can inhibit the virus’s preferred pathway into human cells, and with hydroxychloroquine – the malaria drug touted by Trump — also block the back door, boosting the treatment’s effectiveness.Existing science behind camostat’s mechanism of action and tolerance in patients “is why we were enthusiastic about its potential,” said Elijah Kakani, an assistant professor at the university involved in the research. “However, at this point we need to temper our enthusiasm and be objective in our evaluation of this medication for the problem at hand.” center_img The two compounds are among dozens undergoing testing around the globe and illustrate how the race to develop treatments and vaccines is still wide open despite politicians such as Abe and US President Donald Trump promoting the potential benefits of certain drugs.Gilead Science Inc’s remdesivir has pulled into the lead after promising early trial results prompted emergency approval in the United States and Japan. While remdesivir has shown promise in reducing recovery times of hospitalized patients, the search continues for additional treatment options.Interest in Avigan soared in March after a Chinese official said that it appeared to help patients recover from COVID-19, the flu-like infection caused by the coronavirus. It is now the subject of at least 14 clinical trials. Amidst a global rout in stocks, shares in Fujifilm have shot to record highs.Abe has called for Avigan to be approved for use by the end of this month if these trials are effective – unprecedented speed, particularly for a drug known to cause birth defects.last_img read more

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